Long drives alone can be problematic especially when you are impaired by lack of sleep or the duration of the drive.
This student travelling in Montana reportedly fell asleep and his vehicle hit the end of the guardrail - tearing off 120 linear feet or rail that went through the passenger front headlight and exited out the driver rear window area.
No passengers and no injuries.
Will you be so lucky?
Stop and rest where safe or take short breaks each hour to stretch an exercise. Consider stimulating drinks and eating light. Live another day.